Clinical Validation of Bipolar Disease Genetic Associations

September 24, 2012

The paper entitled “Connection between Gentic and Clinical Data in Bipolar Disorder” is published by PloS ONE and available online here. The paper describes important correlations between clusters of 3-SNP combinations and associated clinical data of the bipolar patients and is a clinical validation of the original paper “Combinations of SNPs Related to Signal Transduction in Bipolar Disorder”.

The process of combinatorial analysis of genetic and clincial data, cluster analysis of the combinations, and permutation tests to verify statistical significance of the findings has been carried out using the GenoKey data mining technology.

Comments are closed.